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Motesanib Diphosphate
Description of:Motesanib Diphosphate
Motesanib Diphosphate potently inhibited VEGF-induced but not bFGF-induced proliferation of HUVECs with IC...
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RAF265(CHIR-265)
Description of:RAF265(CHIR-265)
RAF is a key component of the RAS/RAF/MEK/ERK signal-transduction pathway, which controls cell proliferation, d...
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Sunitinib Malate(SU 11248)
Description of:Sunitinib Malate(SU 11248)
Sunitinib dose-dependently inhibited stem cell factor (SCF)-induced phosphotyrosine levels on KIT (IC...
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PD173074
Description of:PD173074
PD173074 is a potent ATP-competitive, reversible FGFR and VEGFR inhibitor with IC50 of 5, 21.5 and ~100 nM for FGFR3, F...
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Regorafenib(瑞格非尼)
Description of:Regorafenib(瑞格非尼)
BAY 73-4506 is an orally bioavailable multikinase inhibitor targeting both the tumor and its vasculature.
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Brivanib(BMS-540215)
Description of:Brivanib(BMS-540215)
Brivanib (BMS-540215) is a VEGFR -2 inhibitor with an IC50 of 25 nM and Ki of 26 nM.
Theoret...
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SU-5402
Description of:SU-5402
SU 5402 inhibits tyrosine phosphorylation of VEGFR2 and PDGFR in NIH 3T3 cells with IC50 values of 0.4 and 60.9 μM, r...
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SU-6668(TSU-68)
Description of:SU-6668(TSU-68)
TSU-68 (SU6668)is a novel multiple receptor tyrosine kinase inhibitor with IC50 of 2.1 µM, 8 nM and 1.2 &m...
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AV-951(Tivozanib)
Description of:AV-951(Tivozanib)
AV-951 (Tivozanib) is a novel quinoline-urea derivative and now developed by AVEO. AV-951 also inhibits phosph...
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Lenvatinib(E7080)
Description of:Lenvatinib(E7080)
Lenvatinib(E7080) has been evaluated in vitro (pre-clinical) for anti-cancer effects. E7080 suppresses lymph n...
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