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Erlotinib hydrochloride|埃羅替尼
Description of:Erlotinib hydrochloride|埃羅替尼
Erlotinib is an inhibitor of human Epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = ...
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AST-6
Description of:AST-6
AST-6, a rationally designed novel anilino-quinazoline compound, inhibited enzymatic activities of wild type EGFR and ErbB...
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TAK 285
Description of:TAK 285
TAK-285 is currently under clinical development. TAK-285 may have a unique role in the treatment of brain lesions ...
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AEE788
Description of:AEE788
AEE788 demonstrated antiproliferative activity against a range of EGFR and ErbB2-overexpressing cell lines and inhibited ...
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CUDC-101
Description of:CUDC-101
This drug has novel structure incorporating HDAC inhibitory functionality into the pharmacophore of the EGFR and ...
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Afatinib
Description of:Afatinib
Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.
Theor...
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BMS690514
Description of:BMS690514
BMS-690514 is currently under investigation as an oral agent for the treatment of solid tumors. In vitro and in vivo s...
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AG-490
Description of:AG-490
AG490 inhibits the proliferation of several cell types including leukemia cells and fibroblasts. AG490 is also selective ...
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