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ABT-737/ABT737
Description of:ABT-737
ABT-737 induces Bax conformational change but fails to activate Bak or trigger Bax translocation. Coadministration of ro...
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TW-37
Description of:TW-37
TW-37 is Bcl-2 inhibitor (Ki values are 0.29 μM and 1.11 μM for Bcl-2 and Bcl-XL respectively). TW-37 inhibits the a...
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HA14-1
Description of:HA14-1
HA14-1 is cell-permeable inhibitor of Bcl-2 protein (IC50 ~ 9 μM). HA14-1 acts by binding to the surface pocket. Disru...
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Obatoclax
Description of:Obatoclax
Obatoclax is Bcl-2 homology domain-3 (BH3) mimetic,antagonize all antiapoptotic Bcl-2 family proteins (average IC50, 3...
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Navitoclax(ABT-263)
Biological Activity:Navitoclax(ABT-263)
Navitoclax(ABT263) is a small molecule that is designed to restore apoptosis, also known as programmed ...
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Chromatin/Epigenetics
Apoptosis inducer
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