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AZD8330
Description of:AZD8330
AZD8330 (RRY-424704，ARRY-704) specifically inhibits mitogen- activated protein kinase kinase 1 (MEK or MAP/ERK kinase1),...
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BIX02188
Description of:BIX02188
BIX02188 is a MEK5-selective inhibitor with an IC50 of 0.8 ± 1.0 μM.
Theoretical analysis:BIX02188更多>>
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Pimasertib(AS703026)
Description of:AS703026
AS703026 inhibited growth and survival of MM cells (cell IC50 ranging from 0.005 to 2 µM) and cytokine-indu...
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PD98059
Description of:PD98059
PD98059 is inhibitor of mitogen-activated protein kinase kinase (MAPKK / MEK). PD98059 acts by binding to the inac...
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CI1040
Description of:CI1040
CI-1040 is a selective MEK inhibitor (Ki = 300 nM in vitro). CI-1040 suppresses FGF-mediated angiogenesis in vivo and dec...
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Selumetinib (AZD6244)司美替尼
Description of:AZD6244
AZD6244 potently down-regulated the levels of phospho-ERK1/2 and its downstream effector, p-p70S6K, in the MV4-11 and MO...
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GSK1120212
Description of:GSK1120212-Trametinib
MEK inhibitor GSK1120212 specifically binds to and inhibits MEK 1 and 2, resulting in an inhibition of gro...
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PD0325901
Description of:PD0325901
PD0325901 is roughly 500-fold more potent than CI-1040 with respect to its cellular effects on phosphorylation o...
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