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Vemurafenib(維羅非尼)
Description of:Vemurafenib(維羅非尼)
PLX4032 is a highly selective inhibitor of BRAF kinase activity, with an IC50 of 44 nmol/L against V600E-mutan...
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GSK2118436|達(dá)帕菲尼
Description of:SB590885(GSK2118436)|達(dá)帕菲尼
B-590885 is a novel, potent and selective small molecule B-Raf kinase inhibitor with a Ki app of 0.16 ...
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GDC-0879
Description of:GDC-0879
GDC-0879 is a highly selective, novel potent, orally bioavailable B-Raf inhibitor in various in vitro and cell-based as...
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Sorafenib Tosylate(甲磺酸索拉非尼)
Description of:Sorafenib Tosylate(甲磺酸索拉非尼)
Sorafenib (Bay 43-9006) is a novel bi-aryl urea compound that inhibits cell proliferation by targeti...
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PLX-4720
Description of:PLX-4720
PLX4720 preferentially inhibits the active B-RafV600E kinase compared with a broad spectrum of other kinases and potent...
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MEK162(Binimetinib)
Description of:MEK162
MEK162(ARRY-162; ARRY-438162) is an oral, highly selective MEK inhibitor. MEK162(ARRY-162; ARRY-438162) is now being inve...
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GDC-0973|Cobimetinib
Description of:GDC-0973|Cobimetinib
GDC-0973 is also known as mitogen activated protein kinase kinase (MAPKK), is a key component of the RAS/RA...
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BMS777607
Description of:BMS777607
BMS 777607 is a Small-Molecule Met Kinase Inhibitor with an IC50 of < 0.1 μM.
Theoretical analysis:BMS7...
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PD318088
Description of:PD318088
The MEK1 inhibitor PD318088 binds simultaneously with ATP in a region of the kinase active site that is adjacent to the...
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AZD8330
Description of:AZD8330
AZD8330 (RRY-424704，ARRY-704) specifically inhibits mitogen- activated protein kinase kinase 1 (MEK or MAP/ERK kinase1),...
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Antibody-drug Conjugate/ADC Related
MAP4K
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